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Pharmaceutical Portfolio Manager

Company Overview

Tyr is a management consulting and government affairs firm. We partner with our clients to tackle the most important challenges facing their organizations. We value performance and hold ourselves accountable to the highest standards.

Responsibilities and Duties

  • Support BARDA Program Office(s) as a subject matter expert in relevant field of experience(s) for vaccine, therapeutic, and/or antimicrobial advanced development; clinical and/or regulatory policy; and/or manufacturing capacity construction
  •  Provide guidance documents and option papers on key issues related to the area(s) identified;
  •  Review contract proposal and related documents
  •  Provide senior-level briefing(s) to ASPR/BARDA as required
  •  Prepare regular reports to ASPR/BARDA management on various technical issues identified. 
  •  Provide project development level portfolio management and oversight
  •  Develop, implement, and consciously improve Total Life Cycle Cost (TLCC) efforts
  •  Advise the Office of Director on Portfolio Management Decisions
  •  Provide financial analysis on medical countermeasure products that have both commercial and bio defense indications, specifically identifying the sustainability/viability of a commercial market
  • Provide financial analysis to BARDA on the impact of proposed economic incentives
  • Support the implementation of enhanced Portfolio Management for BARDA
  • Ensure alignment of Divisions portfolios with BARDA strategic priorities
  • Evaluate commercial feasibility of a drug development candidate, feasibility of vendor managed inventory and other alternatives to stockpiling MCMs 

Qualifications and Skills

  •  At least 10-15 years of Pharmaceutical Business Development and Portfolio Management experience
  • Industry experience evaluating portfolio strength, conducting business analysis, portfolio rebalancing, and performing financial evaluation of BioPharma assets (e.g. NPV calculations)
  • Experience evaluating outlicensing and in-licensing Drug Development opportunities
  • Experience raising capital (VC, IPO, etc.) to support product development
  • Experience providing strategic planning for BioPharma
  • Experience managing a diverse portfolio of products and development stages (discovery to commercial) that resembles diversity and scale of BARDA portfolio
  • Industry experience preferred with alliance/M&A sourcing experience. Understanding of MCM design, R&D, licensing, and use required. Experience with development, implementing, and oversight of pharmaceutical portfolio Total Life Cycle Cost (TLCC).


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